Takebe and colleagues combine human organoid modeling with genotype-phenotype association studies to disentangle the opposing roles of a gene variant in steatohepatitis. Check out the paper at: http://www.cell.com/cell/fulltext/S00....
M. Kimura, T. Iguchi, K. Iwasawa, A. Dunn, W.L. Thompson, Y. Yoneyama, P. Chaturvedi, A.M. Zorn, M. Wintzinger, M. Quattrocelli, et al. (2022). En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH. Cell 185.
And read more great research at http://www.cell.com/cell/home.
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