Acute Kidney Injury Hospitalization May Increase Risk for Rehospitalization and Death

NIDDK’s Dr. Ivonne H. Schulman talks about her NIH-supported study looking at post-discharge rehospitalization and death rates for people who were hospitalized with acute kidney injury. For more information, visit: https://www.nih.gov/news-events/news-...

Transcript:

DR. SCHULMAN: In this study, we wanted to look at two groups of patients: patients who had had a hospitalization complicated by acute kidney injury compared to matched patients that had been in the hospital but had not experienced an acute kidney injury.

What we did to try and match these two populations is we matched them for diabetes, underlying chronic kidney disease, heart failure, liver disease, cancer, as well as whether their hospital stay had been in an ICU, how many days they had stayed in the hospital, and whether they had had a prior hospitalization within the prior two years.

And what we found is that among patients who have had an acute kidney injury during a hospitalization, those patients subsequently—within 90 days as well as within a year after that acute kidney injury—they had a significantly increased risk for mortality from any cause, as well as an increased risk of hospitalization for any cause, as well as specifically for heart failure, sepsis, pneumonia, myocardial infarction, as well as volume depletion, but really, all types of re-hospitalization were increased and mortality was increased fairly dramatically.


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