THE HERPES SIMPLEX SONG

Published: 05 October 2022
on channel: Neural Academy

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Herpes simplex!
Two thirds of the world it infects!
Usually, there are no symptoms, but effects
Can include skin and mucous membrane lesions!
Found on mouth and tongue or in genital regions!
HSV1 and 2, two types of herpes!
1’s often above waist, 2 below, but no guarantees!
Though it’s most contagious when there are lesions,
It can spread through saliva and through secretions,
Of genitals, even when asymptomatic,
To infect, it must to your receptors stick!
It binds epithelial receptors found within,
Small cracks in mucosa or skin!
This makes the cell internalize this virus thing!
Inside it starts replicating!
And in nearby
sensory neurons virions fly!
Up the axon to the cell body and
The latent cycle begins as was planned!
This virus stays permanently!
In the local nuclei, see?
And occasionally herpes sends
Copies down to the axon ends,
And epithelial cells possess!
With triggers like skin damage, infection, stress!
A prodrome period may occur
A day before the blisters recur!
But fortunately recurrent episodes tend to be less bad
Than the first infection so you can be glad!

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